Dynamic chromatin regulation at Notch target genes
نویسندگان
چکیده
منابع مشابه
Dynamic chromatin regulation at Notch target genes
RBPJ is the central transcription factor that controls the Notch-dependent transcriptional response by coordinating repressing histone H3K27 deacetylation and activating histone H3K4 methylation. Here, we discuss the molecular mechanisms how RBPJ interacts with opposing NCoR/HDAC-corepressing or KMT2D/UTX-coactivating complexes and how this is controlled by phosphorylation of chromatin modifiers.
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ژورنال
عنوان ژورنال: Transcription
سال: 2016
ISSN: 2154-1264,2154-1272
DOI: 10.1080/21541264.2016.1265702